A pioneer in cardiac healthcare, Dr. Shetty and his team have performed over 70,000 major heart surgeries, of which 15,000 were for children, many of them newborns.He manages a large chain of rural clinics in Karnataka and Uttar Pradesh, and helped t he Karnataka government launch the largest micro-health insurance program in the world. He also manages the world's largest telemedicine program through the Indian Space Research Organization (ISRO).